Stemona collinsiae
Stemona collinsiae
Stemona collinsiae, a plant native to certain regions in China, has not been traditionally used for any specific purposes. Scientific investigations have shown promising results; dichloromethane and hexane extracts of this plant demonstrated high activity against Giardia duodenalis in vitro. Additionally, an ethanolic extract from the roots exhibited significant anthelmintic activity against Gnathostoma spinigerum larvae both in vitro and in vivo, with favorable safety profiles observed in rats. The study also developed a method to quantify didehydrostemofoline, a compound found in Stemona collinsiae, in rat plasma, indicating rapid absorption and elimination after oral administration. Furthermore, the dichloromethane root extract showed high contact toxicity against cockroaches and distributed the active compounds to various body parts. No major safety concerns or recorded drug interactions have been noted for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study found that an ethanolic extract of Stemona collinsiae roots showed significant anthelminthic activity against Gnathostoma spinigerum larvae in vitro and in vivo, with favorable safety profiles in rats.
- The study developed a method to quantify didehydrostemofoline in rats' plasma and determined its pharmacokinetic profile after oral administration.
- The dichloromethane and hexane extracts of Stemona collinsiae showed high in vitro activity against Giardia duodenalis.
- Stemona collinsiae dichloromethane root extract showed the highest contact toxicity against cockroach nymphs and adults, with detected distribution of its active compound.
Frequently asked questions
What is Stemona collinsiae?
Stemona collinsiae (Stemona collinsiae) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Stemona collinsiae?
4 sourced findings are recorded for Stemona collinsiae; the strongest carries evidence grade D. For example: The study found that an ethanolic extract of Stemona collinsiae roots showed significant anthelminthic activity against Gnathostoma spinigerum larvae in vitro and in vivo, with favorable safety profiles in rats.
How strong is the evidence for Stemona collinsiae?
The strongest finding for Stemona collinsiae carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Stemona collinsiae safe? What are the side effects?
No major safety issues are recorded for Stemona collinsiae in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Stemona collinsiae interact with medications?
No drug interactions are recorded for Stemona collinsiae in our sources. This does not rule them out — check with a pharmacist.
Is Stemona collinsiae a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 LC-MS/MS analysis of didehydrostemofoline from Stemona collinsiae roots extracts in rats plasma and pharmacokinetics profile after oral administration. literature abstract metadata
- T2 Assessing the efficacy of Stemona collinsiae roots extract against third-stage larvae of Gnathostoma spinigerum and its safety profiles. literature abstract metadata
- T2 Protozoocidal activity of Stemona collinsiae against Giardia duodenalis. literature abstract metadata
- T2 Evaluation of Stemona collinsiae root extracts for topical cockroach control: adulticidal, nymphicidal, and chemical distribution analysis. literature abstract metadata