Symphytum asperum
Symphytum asperum
Symphytum asperum is a traditional medicinal plant that has not been extensively used in any specific tradition. Scientific studies have shown promising results, with high-molecular water-soluble preparations from Symphytum asperum and S. caucasicum exhibiting anticomplementary, antioxidant, and anti-inflammatory activities, as well as modulating B-CLL cell apoptosis and cell cycle progression in vitro. These preparations also demonstrated moderate antibacterial activity and better antifungal activity compared to ketoconazole against certain fungi. Additionally, a technology was developed to extract poly[3-(3,4-dihydroxyphenyl) glyceric acid] from comfrey stems, effectively removing toxic pyrrolizidine alkaloids. The synthesized enantiomers of a glyceric acid derivative showed strong antioxidant activity. No major safety issues or drug interactions have been recorded for Symphytum asperum to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Two high-molecular water-soluble preparations from Symphytum asperum and S. caucasicum show anticomplementary, antioxidant, and antiinflammatory activities and modulate B-CLL cell apoptosis and cell cycle progression in vitro.
- The study found that biopolymers from some Symphytum asperum parts showed moderate antibacterial and better antifungal activities compared to ketoconazole in certain cases.
- The study developed a technology to extract poly[3-(3,4-dihydroxyphenyl) glyceric acid] from comfrey stems, removing toxic pyrrolizidine alkaloids.
- The study synthesized enantiomers of a glyceric acid derivative from Symphytum asperum and S. caucasicum, showing strong antioxidant activity.
Frequently asked questions
What is Symphytum asperum?
Symphytum asperum (Symphytum asperum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Symphytum asperum?
4 sourced findings are recorded for Symphytum asperum; the strongest carries evidence grade D. For example: Two high-molecular water-soluble preparations from Symphytum asperum and S. caucasicum show anticomplementary, antioxidant, and antiinflammatory activities and modulate B-CLL cell apoptosis and cell cycle progression in vitro.
How strong is the evidence for Symphytum asperum?
The strongest finding for Symphytum asperum carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Symphytum asperum safe? What are the side effects?
No major safety issues are recorded for Symphytum asperum in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Symphytum asperum interact with medications?
No drug interactions are recorded for Symphytum asperum in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Symphytum asperum?
Symphytum asperum is also known as: Окопник жёсткий, Consoude hérissée.
Is Symphytum asperum a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Poly[3-(3,4-dihydroxyphenyl)glyceric acid], a new biologically active polymer from Symphytum asperum Lepech. and S. caucasicum Bieb. (Boraginaceae). literature abstract metadata
- T2 Enantioselective synthesis and antioxidant activity of 3-(3,4-dihydroxyphenyl)-glyceric acid--basic monomeric moiety of a biologically active polyether from Symphytum asperum and S. caucasicum. literature abstract metadata
- T2 [Development of technology for the substance of poly[3-(3,4-dihydroxyphenyl) glyceric acid] from Symphytum asperum]. literature abstract metadata
- T2 Antimicrobial Activity of Catechol-Containing Biopolymer Poly[3-(3,4-dihydroxyphenyl)glyceric Acid] from Different Medicinal Plants of Boraginaceae Family. literature abstract metadata