Feverfew
Tanacetum parthenium
Tanacetum parthenium, commonly known as feverfew, originates from traditional medicine practices in Europe and is traditionally used to alleviate migraine symptoms. Scientific evidence suggests that its active compound, parthenolide, may have therapeutic effects on various respiratory diseases and skeletal muscle atrophy, though clinical data are limited. Parthenolide has also shown promise in preventing chronic cephalic hypersensitivity. A systematic review indicates a significant reduction in the frequency of migraines but not in pain severity or associated symptoms. Safety concerns are minimal, with no major issues recorded; similarly, there are no reported drug interactions.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- This review summarizes that parthenolide and its derivatives show significant therapeutic effects in various respiratory diseases but does not provide specific health outcomes.
- Parthenolide alleviates skeletal muscle atrophy by regulating protein homeostasis and inhibiting inflammation.
- Combining low doses of parthenolide and salicin prevented chronic cephalic hypersensitivity and central sensitization in both sexes.
- Feverfew showed a significant reduction in migraine attack frequency but not in pain severity or associated symptoms, according to an updated systematic review and meta-analysis.
Frequently asked questions
What is Feverfew?
Feverfew (Tanacetum parthenium) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Feverfew?
4 sourced findings are recorded for Feverfew; the strongest carries evidence grade D. For example: This review summarizes that parthenolide and its derivatives show significant therapeutic effects in various respiratory diseases but does not provide specific health outcomes.
How strong is the evidence for Feverfew?
The strongest finding for Feverfew carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Feverfew safe? What are the side effects?
No major safety issues are recorded for Feverfew in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Feverfew interact with medications?
No drug interactions are recorded for Feverfew in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Feverfew?
Feverfew is also known as: Пижма девичья, Grande Camomille.
Is Feverfew a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Systematic review and meta-analysis of Tanacetum parthenium: evaluating its efficacy in migraine relief. literature abstract metadata
- T2 Association of parthenolide and salicin as a preventive treatment on a migraine model induced by dural inflammatory soup application. literature abstract metadata
- T2 Parthenolide Attenuates Skeletal Muscle Atrophy Through Regulation of Protein Homeostasis and Inhibition of Inflammation. literature abstract metadata
- T2 Parthenolide and Its Derivatives in the Treatment of Respiratory Tract Diseases: Therapeutic Effects and Molecular Mechanisms. literature abstract metadata