evodia
Tetradium ruticarpum
Tetradium ruticarpum, also known as Wu Zhu Yu or Chinese pepper tree, is a traditional plant used in East Asian medicine. It has been traditionally employed for its purported effects on digestive health and pain relief, though specific uses vary among different cultural practices. Scientific evidence suggests that Tetradium ruticarpum may have potential benefits, particularly in alleviating symptoms of irritable bowel syndrome with diarrhea (IBS-D) and reducing recurrence rates, as shown by some studies involving a combination with Zingiber officinale (ginger). However, more high-quality research is needed to confirm these findings. The extract from Tetradium ruticarpum has also demonstrated increased glutamine uptake in Caco-2 cells, indicating possible gastrointestinal benefits. No major safety concerns or known drug interactions have been recorded for this plant, but further investigation is warranted to fully understand its effects and applications.
- Best evidence
- A
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study developed an environmentally friendly method using custom-designed deep eutectic solvents for extracting alkaloids from Tetradium ruticarpum.
- The combination of Tetradium ruticarpum and Zingiber officinale showed synergistic anti-atherosclerotic effects in mice and VSMCs.
- SSW showed potential in alleviating IBS-D symptoms and reducing recurrence rates, but more high-quality studies are needed.
- A new family, Funiliomycetaceae, is proposed to accommodate the genus Funiliomyces, including the newly described species F. jiangxiensis, based on phylogenetic analyses.
- Tetradium ruticarpum extract and its active ingredient evodiamine increased glutamine uptake in Caco-2 cells.
Frequently asked questions
What is evodia?
evodia (Tetradium ruticarpum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about evodia?
5 sourced findings are recorded for evodia; the strongest carries evidence grade A. For example: The study developed an environmentally friendly method using custom-designed deep eutectic solvents for extracting alkaloids from Tetradium ruticarpum.
How strong is the evidence for evodia?
The strongest finding for evodia carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is evodia safe? What are the side effects?
No major safety issues are recorded for evodia in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does evodia interact with medications?
No drug interactions are recorded for evodia in our sources. This does not rule them out — check with a pharmacist.
Is evodia a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Efficacy and safety of Chinese botanical drug Si Shen Wan in irritable bowel syndrome: a meta-analysis and trial sequential analysis of randomized controlled trials. literature abstract metadata
- T2 Inducible effects of evodiamine on the uptake of glutamine in Caco-2 cells. literature abstract metadata
- T2 The Tetradium ruticarpum-Zingiber officinale Roscoe herb pair inhibits atherogenic events: A study of the synergistic effects and active ingredient combination of a two-herb formula. literature abstract metadata
- T2 Funiliomycetaceae fam. nov. (Amphisphaeriales, Ascomycota) accommodating Funiliomyces, including F. jiangxiensis sp. nov. from Tetradium ruticarpum and ten new combinations. literature abstract metadata
- T2 Environmentally benign and sustainability-optimized extraction of alkaloids from Tetradium ruticarpum using custom-designed deep eutectic solvents. literature abstract metadata