Lesser Meadow-Rue
Thalictrum minus
Thalictrum minus is a plant traditionally not associated with any specific medicinal use. Scientific evidence suggests that it may have potential anti-inflammatory properties, as studies indicate ISO treatment can protect mice from LPS-induced acute lung injury by modulating oxidative stress and inflammatory pathways, though the strength of this evidence remains to be further validated in human trials. Additionally, Thalictrum minus has shown moderate nematicidal activity against S. papillosus larvae with an LC50 value ranging between 0.070-0.079%, indicating its potential for use in nematode control. The plant's complete plastome sequence has been determined and it clusters with Thalictrum minus in phylogenomic analysis, providing insights into its genetic relationships but not directly impacting its medicinal applications. No major safety concerns or recorded drug interactions have been identified to date, though further research is needed to fully understand its potential uses and effects.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- ISO treatment significantly protected mice from LPS-induced ALI, similar to TML, by modulating oxidative stress and inflammatory pathways.
- An ABCB-type transporter, AmABCB1, was identified from Argemone mexicana seeds and shown to have activities with sanguinarine and berberine.
- Thalictrum minus showed moderate nematicidal activity against S. papillosus larvae with an LC50 of 0.070-0.079%.
- The study reports the first complete plastome sequence of Thalictrum aquilegiifolium var. sibiricum, which clusters with Thalictrum minus in phylogenomic analysis.
Frequently asked questions
What is Lesser Meadow-Rue?
Lesser Meadow-Rue (Thalictrum minus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Lesser Meadow-Rue?
4 sourced findings are recorded for Lesser Meadow-Rue; the strongest carries evidence grade D. For example: ISO treatment significantly protected mice from LPS-induced ALI, similar to TML, by modulating oxidative stress and inflammatory pathways.
How strong is the evidence for Lesser Meadow-Rue?
The strongest finding for Lesser Meadow-Rue carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Lesser Meadow-Rue safe? What are the side effects?
No major safety issues are recorded for Lesser Meadow-Rue in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Lesser Meadow-Rue interact with medications?
No drug interactions are recorded for Lesser Meadow-Rue in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Lesser Meadow-Rue?
Lesser Meadow-Rue is also known as: Василистник малый.
Is Lesser Meadow-Rue a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Nematicidal activity of aqueous tinctures of plants against larvae of the nematode Strongyloides papillosus. literature abstract metadata
- T2 AmABCB1, an alkaloid transporter from seeds of Argemone mexicana L (Papaveraceae). literature abstract metadata
- T2 Isoorientin protects lipopolysaccharide-induced acute lung injury in mice via modulating Keap1/Nrf2-HO-1 and NLRP3 inflammasome pathways. literature abstract metadata
- T2 Characterization of the complete plastome of Thalictrum aquilegiifolium var. sibiricum (Ranunculaceae), an annual herb. literature abstract metadata