Annual Devilthorn
Tribulus terrestris
Tribulus terrestris is a plant commonly found in warm and temperate regions around the world. Traditionally, its use has not been extensively documented; however, it is sometimes used in alternative medicine for various conditions such as male sexual dysfunction and female reproductive health issues. Scientific evidence is limited but suggests potential benefits, particularly in reducing hormonal and oxidative markers in polycystic ovary syndrome (PCOS) rats. A case report highlights the risk of Tribulus terrestris causing acute kidney injury, underscoring the need for medical supervision during its use. Additionally, studies indicate that extracts from this plant may have antimicrobial properties and accelerate wound healing in animal models, with identified compounds suggesting possible involvement in ischemic stroke-related processes. Notably, no major safety concerns or drug interactions have been recorded to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- This case report highlights the potential risk of Tribulus terrestris in causing acute kidney injury, emphasizing the need for medical supervision with herbal medication use.
- The study found that polyherbal green-synthesized silver nanoparticles gel showed effective antimicrobial activity and accelerated wound healing in an animal model.
- Tribulus terrestris extract showed reduced hormonal and oxidative markers in PCOS rats, but further human studies are needed.
- Tribulus terrestris ethanol extract showed no sub-acute toxicity and exhibited significant antiurolithiatic activity in rats.
- This study identified 67 compounds in Tribulus terrestris L. extract and 73 absorbed constituents/metabolites, predicting potential involvement of the PI3K/AKT signaling pathway in ischemic stroke-related processes.
Frequently asked questions
What is Annual Devilthorn?
Annual Devilthorn (Tribulus terrestris) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Annual Devilthorn?
5 sourced findings are recorded for Annual Devilthorn; the strongest carries evidence grade D. For example: This case report highlights the potential risk of Tribulus terrestris in causing acute kidney injury, emphasizing the need for medical supervision with herbal medication use.
How strong is the evidence for Annual Devilthorn?
The strongest finding for Annual Devilthorn carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Annual Devilthorn safe? What are the side effects?
No major safety issues are recorded for Annual Devilthorn in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Annual Devilthorn interact with medications?
No drug interactions are recorded for Annual Devilthorn in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Annual Devilthorn?
Annual Devilthorn is also known as: Якорцы стелющиеся, Tribule terrestre.
Is Annual Devilthorn a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Polyherbal green-synthesised silver nanoparticle gel: in vitro antimicrobial activity and in vivo wound healing efficacy using mimosa pudica and tribulus terrestris extracts. literature abstract metadata
- T2 Effect of Tribulus terrestris L. extract in the management of polycystic ovarian syndrome in rat model. literature abstract metadata
- T2 Sub-Acute Toxicity Evaluation and Antiurolithiatic Activity of Tribulus terrestris Ethanol Extract in Rats. literature abstract metadata
- T2 The Effect of Tribulus Terrestris on Acute Kidney Injury: A Case Study. literature abstract metadata
- T2 Systematic profiling of chemical components in Tribulus terrestris L. extract and its absorbed parent compounds/metabolites in rat plasma utilizing UPLC-Q-TOF/MS. literature abstract metadata