Vitex negundo var. cannabifolia
Vitex negundo var. cannabifolia
Vitex negundo var. cannabifolia, a plant native to various regions including Asia and parts of Africa, has not been traditionally used for any specific medicinal purposes. Scientific studies have shown promising results with dietary supplementation using extracts from this plant improving growth performance, blood chemistry, gut morphology, and cecal microbiota in broilers when administered at high doses (3.9 g/kg diet). Additionally, the leaves were found to contain four new phenolic glucosides, one of which exhibited weak nitric oxide inhibition. The fruits yielded 19 compounds, with eight showing potential as inhibitors of nitric oxide production and four demonstrating cytotoxicity in vitro. No significant safety concerns or known drug interactions have been recorded for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study found that dietary supplementation with Vitex negundo L. var. cannabifolia extract improved growth performance, blood chemistry, gut morphology, and cecal microbiota in broilers at a high dose of 3.9 g/kg diet.
- Four new phenolic glucosides were identified from the leaves of Vitex negundo var. cannabifolia, and one compound showed weak inhibition of nitric oxide production.
- The study identified and isolated 19 compounds from Vitex negundo var. cannabifolia fruits, with some showing anti-inflammatory and cytotoxic effects in vitro.
- The study successfully determined simultaneously three lignans in rat samples using UHPLC-Qtrap-MS.
Frequently asked questions
What is Vitex negundo var. cannabifolia?
Vitex negundo var. cannabifolia (Vitex negundo var. cannabifolia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Vitex negundo var. cannabifolia?
4 sourced findings are recorded for Vitex negundo var. cannabifolia; the strongest carries evidence grade D. For example: The study found that dietary supplementation with Vitex negundo L. var. cannabifolia extract improved growth performance, blood chemistry, gut morphology, and cecal microbiota in broilers at a high dose of 3.9 g/kg diet.
How strong is the evidence for Vitex negundo var. cannabifolia?
The strongest finding for Vitex negundo var. cannabifolia carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Vitex negundo var. cannabifolia safe? What are the side effects?
No major safety issues are recorded for Vitex negundo var. cannabifolia in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Vitex negundo var. cannabifolia interact with medications?
No drug interactions are recorded for Vitex negundo var. cannabifolia in our sources. This does not rule them out — check with a pharmacist.
Is Vitex negundo var. cannabifolia a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 [Chemical constituents from the fruits of Vitex negundo var. cannabifolia and their biological activities in vitro]. literature abstract metadata
- T2 Definitely simultaneous determination of three lignans in rat using ultra-high performance liquid chromatography-tandem mass spectrometry. literature abstract metadata
- T2 Phenolic Glucosides from the Leaves of Vitex negundo var. cannabifolia. literature abstract metadata
- T2 Effect of dietary supplementation with Vitex negundo L. var. cannabifolia extract on the growth performance, blood chemistry, gut morphology, and gut microbiota of broilers. literature abstract metadata