Angelicas
Angelica
Angelica, specifically Angelica sinensis (also known as Dong Quai), is a traditional Chinese medicinal plant used in East Asian herbal practices. It has been traditionally employed for various purposes including menstrual disorders and general female health issues, though specific uses vary among different traditions. Scientific evidence indicates that electron beam irradiation can enhance the extraction yield of Angelica sinensis polysaccharides and modify their biofunctional properties in a dose-dependent manner. Nanoparticles derived from Angelica have shown enhanced stability and bioaccessibility for dioscin, a compound with potential medicinal benefits. Metabolomic and transcriptomic analyses have also revealed differences between wild and cultivated Angelica sinensis, highlighting the importance of cultivation methods on chemical composition. However, these findings are preliminary and more research is needed to confirm their broader applicability. Safety concerns for Angelica appear minimal; no major issues have been recorded in existing literature. Similarly, there are currently no reported drug interactions associated with its use. Nonetheless, further studies are warranted to fully understand any potential risks or interactions, especially given the identified adverse event patterns observed in GLP-1 RA therapy for obesity involving some herbs, including Angelica root.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Electron beam irradiation enhanced extraction yield and modified the biofunctional properties of Angelica sinensis polysaccharides in a dose-dependent manner.
- DAZ NPs enhanced dioscin's stability, bioaccessibility, and hepatocyte viability compared to free dioscin.
- Metabolomic and transcriptomic analyses revealed differences in metabolic profiles between wild and cultivated Angelica sinensis, with wild plants showing higher levels of certain compounds.
- Angelica dahurica polysaccharide alleviated hippocampal damage induced by ovariectomy/galactose in rats by enhancing antioxidant capacity and regulating metabolic pathways.
- The study identified Angelica root as one of several herbs potentially associated with adverse events in GLP-1 RA therapy, though findings are exploratory.
- Angelica dahurica extract alleviated muscle atrophy after nerve injury in rats, independently of its analgesic effects.
- Angelica sinensis treatment dose-dependently promoted thymic cortical regeneration in mice with acute thymic involution induced by rapamycin.
Frequently asked questions
What is Angelicas?
Angelicas (Angelica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Angelicas?
7 sourced findings are recorded for Angelicas; the strongest carries evidence grade D. For example: Electron beam irradiation enhanced extraction yield and modified the biofunctional properties of Angelica sinensis polysaccharides in a dose-dependent manner.
How strong is the evidence for Angelicas?
The strongest finding for Angelicas carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Angelicas safe? What are the side effects?
No major safety issues are recorded for Angelicas in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Angelicas interact with medications?
No drug interactions are recorded for Angelicas in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Angelicas?
Angelicas is also known as: Дудник, Angélique.
Is Angelicas a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Nano-assembly of dioscin via zein-Angelica sinensis polysaccharide composite nanocarriers: structure, stability, bioaccessibility and bioactivity. literature abstract metadata
- T2 Efficiently electron beam radiation-induced degradation and extraction of Angelica sinensis polysaccharides and its excellent biofunctional properties. literature abstract metadata
- T2 Integrated metabolomics and transcriptomics reveal metabolite differences between wild and cultivated Angelica sinensis. literature abstract metadata
- T2 [Angelica sinensis promotes thymic cortical regeneration in mice with acute thymic involution induced by short-term rapamycin treatment]. literature abstract metadata
- T2 Angelica dahurica alleviates peripheral nerve injury-induced muscle atrophy via the Phlpp2-Akt-FoxO3α axis independently of analgesia. literature abstract metadata
- T2 Protective effects of Angelica dahurica polysaccharide on alleviating hippocampus injury induced by ovariectomized/D-galactose in rats by inhibiting oxidative stress and its serum metabolomics. literature abstract metadata
- T2 Real-world and computational identification of herbal candidates associated with adverse event patterns in glucagon-like peptide-1 therapy for obesity. literature abstract metadata