Black oil tree
Celastrus paniculatus
Celastrus paniculatus is a plant traditionally associated with certain Asian herbal practices but lacks specific traditional uses documented in the literature. Scientific studies have shown that its seed extract may enhance spatial memory and synaptic plasticity by upregulating key proteins involved in these processes, such as pSer831-GluA1, Arc, and PSD-95, in rat hippocampal tissue. Additionally, a seed fraction F7 has been observed to reduce astrocyte-induced microglial activation through the suppression of CD40/iNOS signaling and pro-inflammatory cytokines. The plant also shows potential for synthesizing zinc oxide nanoparticles with antioxidant, antibacterial, and antifungal properties via an endophytic Aspergillus niger strain. However, clinical validation is necessary to confirm these findings. No major safety concerns or recorded drug interactions have been identified thus far.
- Best evidence
- A
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Celastrus paniculatus seed extract enhanced spatial memory and synaptic plasticity by upregulating pSer831-GluA1, Arc, and PSD-95 expression in the hippocampus of rats.
- This review consolidates current knowledge on Celastrus paniculatus, highlighting its diverse phytochemistry and potential therapeutic effects, though clinical validation is needed.
- Celastrus paniculatus seed fraction F7 attenuated astrocyte-induced microglial activation by suppressing CD40/iNOS signaling and pro-inflammatory cytokines.
- The study found that synthesized copper nanoparticles from Celastrus paniculatus showed antifungal activity and antioxidant enzyme effects in vitro and in vivo.
- The study demonstrates the synthesis of zinc oxide nanoparticles using an endophytic Aspergillus niger strain from Celastrus paniculatus, which exhibit antioxidant, antibacterial, and antifungal activities.
Frequently asked questions
What is Black oil tree?
Black oil tree (Celastrus paniculatus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Black oil tree?
5 sourced findings are recorded for Black oil tree; the strongest carries evidence grade A. For example: Celastrus paniculatus seed extract enhanced spatial memory and synaptic plasticity by upregulating pSer831-GluA1, Arc, and PSD-95 expression in the hippocampus of rats.
How strong is the evidence for Black oil tree?
The strongest finding for Black oil tree carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Black oil tree safe? What are the side effects?
No major safety issues are recorded for Black oil tree in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Black oil tree interact with medications?
No drug interactions are recorded for Black oil tree in our sources. This does not rule them out — check with a pharmacist.
Is Black oil tree a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Enhancement of Memory and Synaptic Plasticity by Celastrus paniculatus Seed Extract: Upregulation of pSer831-GluA1 Trafficking and Arc/PSD-95 Expression in the Hippocampus of Male Rats. literature abstract metadata
- T2 Celastrus paniculatus Willd.: An Extensive Review of Phytochemistry, Traditional Uses, Pharmacological Potential, and Safety Profile. literature abstract metadata
- T2 Antimicrobial and antioxidant activity of green synthesized copper nanoparticles. literature abstract metadata
- T2 TLC-Derived High-Polar Fractions of Celastrus paniculatus Seeds Attenuate Astrocyte-Driven Microglial Activation Through Suppression of CD40/iNOS Signaling and Pro-Inflammatory Cytokines. literature abstract metadata
- T2 Mycogenic synthesis of ZnO nanoparticles using an endophytic Aspergillus niger isolate from Celastrus paniculatus: evaluation of multifunctional bioactivity for agricultural and antimicrobial applications. literature abstract metadata