Clematis hexapetala
Clematis hexapetala
Clematis hexapetala is a plant traditionally used for various conditions, though specific uses are not well-documented. Scientific studies have shown that its aqueous extract can reduce serum uric acid levels and improve renal function in hyperuricemic mice by regulating the PI3K/AKT/NF-κB pathway. Additionally, both crude and wine processed Clematis hexapetala demonstrated anti-inflammatory effects by inhibiting glycolysis and modulating gut microbiota in rheumatoid arthritis rats. While these findings suggest potential therapeutic benefits, further research is needed due to limited pharmacological studies compared to other Clematis species. No major safety issues or drug interactions have been recorded for this plant, but comprehensive clinical trials are required to fully understand its efficacy and safety profile.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The aqueous extract of Clematis hexapetala significantly reduced serum uric acid levels and improved renal function in hyperuricemic mice by regulating the PI3K/AKT/NF-κB pathway.
- Crude and wine processed Clematis hexapetala showed anti-inflammatory effects by inhibiting glycolysis and modulating gut microbiota in rheumatoid arthritis rats.
- The study reviewed uses, chemical compositions, pharmacological activities, and toxicology of Clematis hexapetala, but did not find conclusive health effects.
- The complete chloroplast genome of Clematis hexapetala was sequenced, revealing a typical quadripartite structure with 135 encoded genes, placing it closely related to C. taeguensis in phylogenetic analysis.
Frequently asked questions
What is Clematis hexapetala?
Clematis hexapetala (Clematis hexapetala) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Clematis hexapetala?
4 sourced findings are recorded for Clematis hexapetala; the strongest carries evidence grade D. For example: The aqueous extract of Clematis hexapetala significantly reduced serum uric acid levels and improved renal function in hyperuricemic mice by regulating the PI3K/AKT/NF-κB pathway.
How strong is the evidence for Clematis hexapetala?
The strongest finding for Clematis hexapetala carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Clematis hexapetala safe? What are the side effects?
No major safety issues are recorded for Clematis hexapetala in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Clematis hexapetala interact with medications?
No drug interactions are recorded for Clematis hexapetala in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Clematis hexapetala?
Clematis hexapetala is also known as: Ломонос шестилепестковый.
Is Clematis hexapetala a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Uses, chemical compositions, pharmacological activities and toxicology of Clematidis Radix et Rhizome- a Review. literature abstract metadata
- T2 Thermal and wine processing enhanced Clematidis Radix et Rhizoma ameliorate collagen Ⅱ induced rheumatoid arthritis in rats. literature abstract metadata
- T2 The complete chloroplast genome of Clematis hexapetala (Ranunculaceae) and its phylogenetic analysis. literature abstract metadata
- T2 Extract of Clematis hexapetala regulates uric acid metabolism, alleviates renal inflammation and fibrosis via the PI3K/AKT/NF-κB signaling pathway, and improves hyperuricemia in mice. literature abstract metadata