Clematis terniflora var. mandshurica
Clematis terniflora var. mandshurica
Clematis terniflora var. manshurica, also known as Japanese Clematis or Manchurian Clematis, is a plant native to East Asia. While traditional uses for this plant are not well-documented in historical practices, scientific research has shown some promising results. Studies have identified compounds from its roots and rhizomes that exhibit varying inhibitory effects on TNF-α-induced cell proliferation, suggesting potential anti-inflammatory properties. Additionally, JOINS tablets containing extracts from Clematis manshurica showed a greater reduction in low back pain compared to the control group after 6 months of use. Research has also identified nine new oleanane-type triterpenoid saponins with anti-inflammatory activity by inhibiting NF-κB activation. Notably, SKCPT (a formulation from Clematis terniflora var. manshurica) was found to be non-inferior to celecoxib in treating knee osteoarthritis and had a similar safety profile. To date, no major safety issues or significant drug interactions have been recorded for this plant.
- Best evidence
- B
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Compounds from Clematis manshurica roots and rhizomes showed varying inhibitory effects on TNF-α-induced cell proliferation.
- The study found that the JOINS tablet group showed a greater reduction in low back pain compared to the control group after 6 months.
- Nine new oleanane-type triterpenoid saponins were identified from Clematis terniflora var. manshurica, with four showing strong anti-inflammatory activity by inhibiting NF-κB activation.
- The study found that SKCPT was non-inferior to celecoxib in treating knee osteoarthritis and had a similar safety profile.
Frequently asked questions
What is Clematis terniflora var. mandshurica?
Clematis terniflora var. mandshurica (Clematis terniflora var. mandshurica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Clematis terniflora var. mandshurica?
4 sourced findings are recorded for Clematis terniflora var. mandshurica; the strongest carries evidence grade B. For example: Compounds from Clematis manshurica roots and rhizomes showed varying inhibitory effects on TNF-α-induced cell proliferation.
How strong is the evidence for Clematis terniflora var. mandshurica?
The strongest finding for Clematis terniflora var. mandshurica carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Clematis terniflora var. mandshurica safe? What are the side effects?
No major safety issues are recorded for Clematis terniflora var. mandshurica in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Clematis terniflora var. mandshurica interact with medications?
No drug interactions are recorded for Clematis terniflora var. mandshurica in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Clematis terniflora var. mandshurica?
Clematis terniflora var. mandshurica is also known as: Ломонос маньчжурский.
Is Clematis terniflora var. mandshurica a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Efficacy and safety of SKCPT in patients with knee osteoarthritis: A multicenter, randomized, double-blinded, active-controlled phase III clinical trial. literature abstract metadata
- T2 Efficacy of JOINS Tablet for Lumbar Spinal Stenosis: Prospective, Randomized, Open-Label Clinical Trial. literature abstract metadata
- T2 Triterpenoid saponins from the roots and rhizomes of Clematis terniflora var. manshurica (Rupr.) Ohwi and their anti-inflammatory activities. literature abstract metadata
- T2 Triterpenoid saponins from Clematis manshurica inhibiting the inflammatory responses of TNF-α-stimulated MH7A cells. literature abstract metadata