Crataegus
Crataegus
Crataegus, commonly known as hawthorn, is a traditional medicinal plant with roots in various European and Asian herbal practices. It has been traditionally used for cardiovascular support, but specific uses vary widely across different cultures without clear documentation. Scientific evidence suggests that optimal extraction conditions can enhance the bioactive compound content of Crataegus monogyna flowering branches, potentially increasing their biological activities. Additionally, a polyherbal mixture including Crataegus pinnatifida has shown promise in reducing diarrhea incidence in preweaning calves. While single-cell transcriptomic studies have provided insights into hawthorn leaf biology, the direct impact on human health remains to be fully elucidated. There are no major safety concerns or recorded drug interactions noted for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study found that optimal extraction conditions significantly enhanced the bioactive compound content and biological activities of Crataegus monogyna flowering branches.
- The study generated the first single-cell transcriptomic atlas of hawthorn leaves, identifying nine canonical cell types and their specific gene expressions.
- Supplementation with a polyherbal mixture including Crataegus pinnatifida significantly decreased diarrhea occurrence in preweaning calves.
- UA from hawthorn enhanced THSG absorption and altered its metabolism by regulating UGT1A1 expression and miR-150-5p levels.
Frequently asked questions
What is Crataegus?
Crataegus (Crataegus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Crataegus?
4 sourced findings are recorded for Crataegus; the strongest carries evidence grade D. For example: The study found that optimal extraction conditions significantly enhanced the bioactive compound content and biological activities of Crataegus monogyna flowering branches.
How strong is the evidence for Crataegus?
The strongest finding for Crataegus carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Crataegus safe? What are the side effects?
No major safety issues are recorded for Crataegus in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Crataegus interact with medications?
No drug interactions are recorded for Crataegus in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Crataegus?
Crataegus is also known as: боярышник, aubépine.
Is Crataegus a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Optimization of ultrasound-assisted extraction and biological activities of Crataegus monogyna Jacq. flowering branches using experimental design and artificial neural networks. literature abstract metadata
- T2 Enhancement of ursolic acid (UA), an active ingredient in hawthorn, on the uptake and metabolism of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (THSG) derived from Polygonum multiflorum. literature abstract metadata
- T2 Single-cell RNA-sequencing profiles reveal the developmental landscape of hawthorn leaves. literature abstract metadata
- T2 Mechanism of a polyherbal mixture alleviates calf diarrhea: an integrated network pharmacology, metabolomics, and microbiome study. literature abstract metadata