Hairy Thorn-apple

Datura wrightii

Datura wrightii, also known as Jimsonweed or Sacred Datura, is a traditional medicine plant native to North America. While its use in specific traditions and for particular ailments has not been extensively documented, it has been associated with various cultural practices, often involving caution due to its potent alkaloids. Scientific studies have primarily focused on the plant's genetic makeup and interactions rather than its medicinal uses. Research indicates that Datura wrightii contains over 3000 differentially expressed genes related to herbivory, suggesting complex interactions with insects. Additionally, a study found that ants preferentially remove seeds with heavier elaiosomes, highlighting both benefits and costs in seed dispersal mechanisms. Another study revealed thousands of differentially expressed genes associated with plant-insect interactions, particularly through osmolality maintenance under dry conditions by moths. Safety records for Datura wrightii are currently unremarkable; no major issues have been reported. However, due to its potent nature and potential toxicity, it is important to exercise extreme caution. There are no recorded drug interactions with this plant at present.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • The study found thousands of genes differentially expressed between individuals feeding on Datura wrightii and Nicotiana attenuata. D PMID
  • The study found over 3000 differentially expressed genes associated with herbivory in Datura wrightii. D PMID
  • Ants removed Datura wrightii seeds with heavier elaiosomes and lighter seeds more quickly, supporting that both benefits and costs influence seed dispersal. D PMID
  • Moths maintained healthy osmolality with nectar feeding, but dehydration led to osmotic stress and reduced survival. D PMID

Frequently asked questions

What is Hairy Thorn-apple?

Hairy Thorn-apple (Datura wrightii) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Hairy Thorn-apple?

4 sourced findings are recorded for Hairy Thorn-apple; the strongest carries evidence grade D. For example: The study found thousands of genes differentially expressed between individuals feeding on Datura wrightii and Nicotiana attenuata.

How strong is the evidence for Hairy Thorn-apple?

The strongest finding for Hairy Thorn-apple carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Hairy Thorn-apple safe? What are the side effects?

No major safety issues are recorded for Hairy Thorn-apple in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Hairy Thorn-apple interact with medications?

No drug interactions are recorded for Hairy Thorn-apple in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Hairy Thorn-apple?

Hairy Thorn-apple is also known as: Datura de Wright.

Is Hairy Thorn-apple a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 A de novo long-read genome assembly of the sacred datura plant (Datura wrightii) reveals a role of tandem gene duplications in the evolution of herbivore-defense response. literature abstract metadata
  2. T2 A pooled-sample draft genome assembly provides insights into host plant-specific transcriptional responses of a Solanaceae-specializing pest, Tupiocoris notatus (Hemiptera: Miridae). literature abstract metadata
  3. T2 Dying of thirst: Osmoregulation by a hawkmoth pollinator in response to variability in ambient humidity and nectar availability. literature abstract metadata
  4. T2 Both costs and benefits determine the removal of Datura (Solanaceae) seeds by seed-dispersing ants. literature abstract metadata