Davallia formosana

Davallia formosana

Davallia formosana, a fern commonly found in East Asia, has not been traditionally used for medicinal purposes. Scientific research indicates potential benefits such as anti-proliferative effects on prostate cancer cells and anti-inflammatory properties in models of arthritis. Extracts also showed osteogenic activity and reduced bone loss in ovariectomized mice, suggesting possible applications in bone health. No major safety concerns or known drug interactions have been reported, but further human studies are needed to confirm these findings comprehensively.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • ECAP from D. formosana inhibited RANKL-induced osteoclastogenesis and reduced bone loss in ovariectomized mice. D PMID
  • Davallia formosana ethanol extract suppressed proliferation, migration, invasion, lipogenesis, and androgen receptor expression in prostate cancer cells. D PMID
  • ECAP reduced paw swelling and arthritis severity score, decreased pro-inflammatory cytokines, increased anti-inflammatory cytokines, and suppressed NO production in mice with collagen-induced arthritis. D PMID
  • Davallia formosana extracts showed increased osteoblastic activity in MC3T3-E1 cells compared to controls. D PMID

Frequently asked questions

What is Davallia formosana?

Davallia formosana (Davallia formosana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Davallia formosana?

4 sourced findings are recorded for Davallia formosana; the strongest carries evidence grade D. For example: ECAP from D. formosana inhibited RANKL-induced osteoclastogenesis and reduced bone loss in ovariectomized mice.

How strong is the evidence for Davallia formosana?

The strongest finding for Davallia formosana carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Davallia formosana safe? What are the side effects?

No major safety issues are recorded for Davallia formosana in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Davallia formosana interact with medications?

No drug interactions are recorded for Davallia formosana in our sources. This does not rule them out — check with a pharmacist.

Is Davallia formosana a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 (-)-Epicatechin 3-O-β-D-allopyranoside prevent ovariectomy-induced bone loss in mice by suppressing RANKL-induced NF-κB and NFATc-1 signaling pathways. literature abstract metadata
  2. T2 Effects of Davallia formosana Hayata Water and Alcohol Extracts on Osteoblastic MC3T3-E1 Cells. literature abstract metadata
  3. T2 Anti-arthritic and anti-inflammatory effects of (-)-Epicatechin-3-O-β-d-allopyranoside, a constituent of Davallia formosana. literature abstract metadata
  4. T2 Emerging Therapeutic Activity of Davallia formosana on Prostate Cancer Cells through Coordinated Blockade of Lipogenesis and Androgen Receptor Expression. literature abstract metadata