Squirrel’s-foot fern
Davallia mariesii
Davallia mariesii, commonly known as the maidenhair spleenwort, is a traditional medicinal plant native to temperate regions of Europe and Asia. While its use in traditional medicine has not been extensively documented, it has shown promise in modern scientific research. Studies suggest that kidney tonic herbs, including Davallia mariesii, may increase bone mineral density and reduce fracture incidence in primary osteoporosis patients; however, further research is needed to confirm these findings. Additionally, the plant extract demonstrated anti-influenza activity by inhibiting viral attachment, penetration, and cell-cell fusion during early infection stages. In vitro studies also indicated potential neuroprotective effects through reduced amyloid-beta (Aβ) production and aggregation, which may mitigate memory impairment. Regarding safety, no major issues have been recorded for Davallia mariesii, and there are currently no known drug interactions associated with its use.
- Best evidence
- A
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The meta-analysis suggested that kidney tonic herbs may increase bone mineral density and reduce fracture incidence in primary osteoporosis patients, but more research is needed.
- Davallia mariesii extract inhibited influenza A virus during early infection stages by hindering viral attachment, penetration, and cell-cell fusion.
- DMH improved bone mineral density and inhibited osteoclast differentiation in OVX mice, enhancing bone formation in primary human osteoblasts.
- The ethanol extract of Davallia mariesii roots reduced Aβ production and aggregation in vitro and showed potential to mitigate memory impairment in vivo, suggesting possible neuroprotective effects.
Frequently asked questions
What is Squirrel’s-foot fern?
Squirrel’s-foot fern (Davallia mariesii) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Squirrel’s-foot fern?
4 sourced findings are recorded for Squirrel’s-foot fern; the strongest carries evidence grade A. For example: The meta-analysis suggested that kidney tonic herbs may increase bone mineral density and reduce fracture incidence in primary osteoporosis patients, but more research is needed.
How strong is the evidence for Squirrel’s-foot fern?
The strongest finding for Squirrel’s-foot fern carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Squirrel’s-foot fern safe? What are the side effects?
No major safety issues are recorded for Squirrel’s-foot fern in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Squirrel’s-foot fern interact with medications?
No drug interactions are recorded for Squirrel’s-foot fern in our sources. This does not rule them out — check with a pharmacist.
Is Squirrel’s-foot fern a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 In vivo and in vitro evaluation of the osteogenic potential of Davallia mariesii T. Moore ex Baker. literature abstract metadata
- T2 Effects of kidney tonic herbs for primary osteoporosis: A systematic review and meta-analysis. literature abstract metadata
- T2 Neuroprotective Effects of Davallia mariesii Roots and Its Active Constituents on Scopolamine-Induced Memory Impairment in In Vivo and In Vitro Studies. literature abstract metadata
- T2 Novel Anti-Viral Properties of the Herbal Extract of Davallia mariesii against Influenza A Virus. literature abstract metadata