Euphorbia peplus
Euphorbia peplus
Euphorbia peplus, commonly known as common spurge, is a plant that has not been traditionally used in any specific medical or healing practices. Scientific studies have identified 13 ingenane-type compounds from Euphorbia peplus, with some showing potential for activating autophagic flux. Additionally, four diterpenoids were isolated, one of which increased ABCA1 levels in BV-2 cells and may target PPARγ. While the study on herbicide targets suggests possible use in sustainable bio-based weed control, the broader scientific evidence is limited to these findings. No major safety issues or drug interactions have been recorded for Euphorbia peplus, but further research is necessary to fully understand its potential applications and effects.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study identified 13 ingenane-type compounds from Euphorbia peplus, with 17-O-benzoyl-20-deoxyingenol showing significant activation of autophagic flux at concentrations of 10 μM and 40 μM.
- Four diterpenoids were isolated from Euphorbia peplus, with one (compound 4) increasing ABCA1 levels in BV-2 cells and potentially targeting PPARγ.
- Selected phytochemicals from Genista ulicina showed potential as inhibitors of key herbicide targets, indicating possible use in sustainable bio-based weed control.
- The study identified enzymes involved in the biosynthesis of ingenol-3-angelate from Euphorbia peplus.
- The study presents a genome assembly of Euphorbia peplus, including 8 chromosomal pseudomolecules and mitochondrial/plastid genomes.
Frequently asked questions
What is Euphorbia peplus?
Euphorbia peplus (Euphorbia peplus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Euphorbia peplus?
5 sourced findings are recorded for Euphorbia peplus; the strongest carries evidence grade D. For example: The study identified 13 ingenane-type compounds from Euphorbia peplus, with 17-O-benzoyl-20-deoxyingenol showing significant activation of autophagic flux at concentrations of 10 μM and 40 μM.
How strong is the evidence for Euphorbia peplus?
The strongest finding for Euphorbia peplus carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Euphorbia peplus safe? What are the side effects?
No major safety issues are recorded for Euphorbia peplus in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Euphorbia peplus interact with medications?
No drug interactions are recorded for Euphorbia peplus in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Euphorbia peplus?
Euphorbia peplus is also known as: Молочай огородный, Euphorbe des jardins.
Is Euphorbia peplus a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 The genome sequence of petty spurge, Euphorbia peplus L. (Euphorbiaceae). literature abstract metadata
- T2 Identification of BAHD-acyltransferase enzymes involved in ingenane diterpenoid biosynthesis. literature abstract metadata
- T2 Exploring the Potential of Genista ulicina Phytochemicals as Natural Biocontrol Agents: A Comparative In Vitro and In Silico Analysis. literature abstract metadata
- T2 Euphorbia diterpenoids from Euphorbia peplus possessing anti-Alzheimer's activity via targeting PPARγ and upregulating the level of ABCA1. literature abstract metadata
- T2 Ingenane Diterpenoids from Euphorbia peplus: Structure Elucidation and Autophagic Flux Activation Activity. literature abstract metadata