licorice

Glycyrrhiza glabra

Glycyrrhiza glabra, commonly known as licorice, is a traditional plant used in various cultural practices. While its specific uses are not well-documented in historical traditions, it has been employed for its sweet taste and potential medicinal properties. Scientific evidence suggests that licorice may have some benefits, particularly in managing respiratory conditions due to its mucilage content and iridoid compounds. Additionally, preclinical studies indicate possible cognitive benefits and metabolic improvements in women with polycystic ovary syndrome (PCOS), though more standardized research is needed to confirm these findings. In terms of safety, no major issues have been recorded, and there are currently no known significant drug interactions associated with licorice use.

At a glance
Best evidence
B
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • The study assessed the potential of licorice supplementation to modulate metabolic and inflammatory parameters in women with PCOS. B PMID
  • Glycyrrhiza glabra, among other plants, shows potential in managing chronic respiratory conditions through mechanisms involving mucilage and iridoid compounds. D PMID
  • Glycyrrhiza glabra shows potential as a complementary approach for cognitive support and neuroprotection based on preclinical evidence, but more large-scale clinical studies are needed. D PMID
  • HP and GE preserved cardiac mitochondrial redox homeostasis in E2 deficiency by modulating MAO-A and ERβ. D PMID
  • The review identified common herbal pairs containing Paeoniae Radix Alba, with Glycyrrhiza glabra frequently paired, though no specific health effects are stated. D PMID

Frequently asked questions

What is licorice?

licorice (Glycyrrhiza glabra) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about licorice?

5 sourced findings are recorded for licorice; the strongest carries evidence grade B. For example: The study assessed the potential of licorice supplementation to modulate metabolic and inflammatory parameters in women with PCOS.

How strong is the evidence for licorice?

The strongest finding for licorice carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).

Is licorice safe? What are the side effects?

No major safety issues are recorded for licorice in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does licorice interact with medications?

No drug interactions are recorded for licorice in our sources. This does not rule them out — check with a pharmacist.

What are the common names of licorice?

licorice is also known as: солодка, Réglisse.

Is licorice a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Therapeutic potential of Glycyrrhiza glabra (licorice) in modulating metabolic and inflammatory parameters in women with PCOS. literature abstract metadata
  2. T2 Herbal pairs containing Paeoniae Radix Alba: A review of pharmacological activities, clinical applications, and data mining analysis of compatibility patterns. literature abstract metadata
  3. T2 Hypericum perforatum L. and Glycyrrhiza glabra L. preserve cardiac mitochondrial redox homeostasis in E2 deficiency via ERβ-MAO-A modulation. literature abstract metadata
  4. T2 Traditional Respiratory Remedies From Anatolia: Ethnobotanical Insights and Bioactive Properties. literature abstract metadata
  5. T2 Herbal Neurotherapeutics for Cognitive Disorders: Integrative Mechanisms Linking Neurotransmitter Systems, Neurodegeneration, and the Gut-Brain Axis. literature abstract metadata