Kopsia
Kopsia
Kopsia is a genus of plants traditionally not used in any known medicinal practices. Scientific studies have focused on its chemical composition, particularly the isolation and synthesis of various alkaloids from Kopsia species. Five monoterpenoid indole alkaloids were synthesized from the Kopsia genus using non-biomimetic strategies, with ten aspidofractinine-type alkaloids identified in Kopsia officinalis roots, showing potent cytotoxic activity against certain cancer cell lines. Four bisindole alkaloids isolated from Kopsia hainanensis demonstrated moderate inhibitory effects on lung cancer cells, though the potencies varied. No significant safety concerns or drug interactions have been recorded for this plant genus.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Ten aspidofractinine-type alkaloids were identified from Kopsia officinalis roots, with one showing potential cytotoxic activity against certain cancer cell lines.
- The study achieved the divergent total synthesis of five monoterpenoid indole alkaloids from Kopsia using a non-biomimetic strategy.
- Kopsia alkaloids, including kopsiarborine B and kopsifine, showed cytotoxic activity against various cancer cell lines.
- Kopsileuconines A-D, bisindole alkaloids from Kopsia hainanensis, showed cytotoxic activity against lung cancer cells.
Frequently asked questions
What is Kopsia?
Kopsia (Kopsia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Kopsia?
4 sourced findings are recorded for Kopsia; the strongest carries evidence grade D. For example: Ten aspidofractinine-type alkaloids were identified from Kopsia officinalis roots, with one showing potential cytotoxic activity against certain cancer cell lines.
How strong is the evidence for Kopsia?
The strongest finding for Kopsia carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Kopsia safe? What are the side effects?
No major safety issues are recorded for Kopsia in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Kopsia interact with medications?
No drug interactions are recorded for Kopsia in our sources. This does not rule them out — check with a pharmacist.
Is Kopsia a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Kopsileuconines A-D: Bisindole alkaloids with cytotoxic activity from Kopsia hainanensis. literature abstract metadata
- T2 Divergent Synthesis of Kopsia and Structurally Related Monoterpenoid Indole Alkaloids: A Non-biomimetic Strategy. literature abstract metadata
- T2 New aspidofractinine-type alkaloids with cytotoxic activity from the roots of Kopsia officinalis. literature abstract metadata
- T2 Unlocking the cytotoxic potential of Apocynaceae monoterpene indole and bis-indole alkaloids: a review. literature abstract metadata