Stephania pierrei
Stephania pierrei
Stephania pierrei is a plant traditionally unrecorded for medicinal use. Scientific evidence suggests that its calli can produce secondary metabolites such as cepharantine, tetrandrine, and fangchinoline, indicating potential for sustainable phytochemical production. Additionally, oxocrebanine from the tubers of Stephania pierrei has shown promise in reducing inflammation and protecting against acute lung injury by inhibiting multiple inflammatory pathways. Eight new alkaloids were isolated from this plant, some displaying stronger cholinesterase inhibitory activities compared to galanthamine. Safety concerns are currently unrecorded, with no major issues noted. There are also no reported drug interactions associated with Stephania pierrei.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Oxocrebanine from Stephania pierrei tubers reduces inflammation and protects against LPS-induced acute lung injury in mice by inhibiting multiple inflammatory pathways.
- Eight new alkaloids were isolated from Stephania pierrei, and some showed stronger cholinesterase inhibitory activities compared to galanthamine.
- The study found that calli of Stephania pierrei can produce secondary metabolites including cepharantine, tetrandrine, and fangchinoline with potential for sustainable phytochemical production.
- Oxocrebanine from Stephania pierrei tubers significantly inhibited inflammatory responses by downregulating multiple signalling pathways in macrophages.
Frequently asked questions
What is Stephania pierrei?
Stephania pierrei (Stephania pierrei) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Stephania pierrei?
4 sourced findings are recorded for Stephania pierrei; the strongest carries evidence grade D. For example: Oxocrebanine from Stephania pierrei tubers reduces inflammation and protects against LPS-induced acute lung injury in mice by inhibiting multiple inflammatory pathways.
How strong is the evidence for Stephania pierrei?
The strongest finding for Stephania pierrei carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Stephania pierrei safe? What are the side effects?
No major safety issues are recorded for Stephania pierrei in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Stephania pierrei interact with medications?
No drug interactions are recorded for Stephania pierrei in our sources. This does not rule them out — check with a pharmacist.
Is Stephania pierrei a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Stephapierrines A-H, new tetrahydroprotoberberine and aporphine alkaloids from the tubers of Stephania pierrei Diels and their anti-cholinesterase activities. literature abstract metadata
- T2 Oxocrebanine from Stephania pierrei exerts macrophage anti-inflammatory effects by downregulating the NF-κB, MAPK, and PI3K/Akt signalling pathways. literature abstract metadata
- T2 Protective effects of Stephania pierrei tuber-derived oxocrebanine against LPS-induced acute lung injury in mice. literature abstract metadata
- T2 In vitro propagation of Stephania pierrei diels and exploration of its potential as sustainable phytochemical production from tuber and callus. literature abstract metadata