Sophora pachycarpa
Sophora pachycarpa
Sophora pachycarpa, a plant traditionally not associated with any known medicinal practices, has shown promise in scientific research. Studies have indicated that its seed extract may offer protection against liver and kidney toxicity caused by carbon tetrachloride in rats. Additionally, the seeds demonstrated notable antidiabetic activity, though their effect on blood sugar regulation was comparable to metformin. The roots of Sophora pachycarpa contain alopecurones J and P, which exhibited cytotoxic effects on MCF-7 breast cancer cells through potential involvement with the Wnt signaling pathway. Alopecurone J also showed potent cytotoxic and pan-HDAC inhibitory activities among tested compounds from the plant's roots. No major safety concerns or known drug interactions have been recorded for Sophora pachycarpa, though further research is necessary to fully understand its medicinal properties and potential applications.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study found that Sophora pachycarpa seed extract showed a protective effect against carbon tetrachloride-induced liver and kidney toxicity in rats.
- Alopecurones J and P exhibited cytotoxic effects against MCF-7 breast cancer cells via potential Wnt signaling pathway involvement.
- The study identified the chemical composition of Sophora pachycarpa seeds extract and found it exhibited notable antidiabetic activity, though its effect on blood sugar levels was similar to metformin.
- Alopecurone J exhibited potent cytotoxic and pan-HDAC inhibitory activities among tested compounds from Sophora pachycarpa roots.
Frequently asked questions
What is Sophora pachycarpa?
Sophora pachycarpa (Sophora pachycarpa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Sophora pachycarpa?
4 sourced findings are recorded for Sophora pachycarpa; the strongest carries evidence grade D. For example: The study found that Sophora pachycarpa seed extract showed a protective effect against carbon tetrachloride-induced liver and kidney toxicity in rats.
How strong is the evidence for Sophora pachycarpa?
The strongest finding for Sophora pachycarpa carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Sophora pachycarpa safe? What are the side effects?
No major safety issues are recorded for Sophora pachycarpa in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Sophora pachycarpa interact with medications?
No drug interactions are recorded for Sophora pachycarpa in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Sophora pachycarpa?
Sophora pachycarpa is also known as: Софора толстоплодная.
Is Sophora pachycarpa a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Absolute configuration and anti-cancer effect of prenylated flavonoids and flavonostilbenes from Sophora pachycarpa: Possible involvement of Wnt signaling pathway. literature abstract metadata
- T2 Histone Deacetylase Inhibitory and Cytotoxic Activities of the Constituents from the Roots of Sophora Pachycarpa. literature abstract metadata
- T2 Antidiabetic effect of Sophora pachycarpa seeds extract in streptozotocin-induced diabetic mice: a statistical evaluation. literature abstract metadata
- T2 Protective effect of Sophora pachycarpa seed extract on carbon tetrachloride-induced toxicity in rats. literature abstract metadata